OrangerV1, Main, Exploration, bibRecord, 000E86

Dietary intake of melatonin from tropical fruit altered urinary excretion of 6-sulfatoxymelatonin in healthy volunteers.

Identifieur interne : 000E86 ( Main/Exploration ); précédent : 000E85; suivant : 000E87

Dietary intake of melatonin from tropical fruit altered urinary excretion of 6-sulfatoxymelatonin in healthy volunteers.

Auteurs : Nutjaree Pratheepawanit Johns [Thaïlande] ; Jeffrey Johns ; Supatra Porasuphatana ; Preeyaporn Plaimee ; Manit Sae-Teaw

Source :

Journal of agricultural and food chemistry [ 1520-5118 ] ; 2013.

RBID : pubmed:23252791

English descriptors

KwdEn :
- Adolescent, Adult, Ananas (chemistry), Citrus sinensis (chemistry), Cross-Over Studies, Diet, Female, Fruit (chemistry), Health Promotion, Humans, Male, Melatonin (administration & dosage), Melatonin (analogs & derivatives), Melatonin (urine), Musa (chemistry), Tropical Climate, Young Adult.
MESH :
- chemical , administration & dosage : Melatonin.
- chemical , analogs & derivatives : Melatonin.
- chemistry : Ananas, Citrus sinensis, Fruit, Musa.
- chemical , urine : Melatonin.
- Adolescent, Adult, Cross-Over Studies, Diet, Female, Health Promotion, Humans, Male, Tropical Climate, Young Adult.

Abstract

This study assessed the melatonin content of six tropical fruits and examined whether human consumption could contribute to dietary melatonin as measured by 6-sulfatoxymelatonin (aMT6-s, a marker of circulating melatonin in the body). Melatonin was extracted using methanol and analyzed by high-performance liquid chromatography. In a clinical crossover study, 30 healthy volunteers consumed selected fruits one at a time, with a 1week wash-out period between fruits, until completing all six fruits. Most fruits had moderate melatonin content. Significant increases in urine aMT6-s concentrations were seen after the consumption of pineapple (266%, p = 0.004), banana (180%, p = 0.001), and orange (47%, p = 0.007). The need to analyze melatonin both in fruit and as in vivo uptake was demonstrated. Further study is warranted regarding the clinical effect of fruit consumption in people with age-related melatonin reduction problems such as sleeplessness and illnesses involving oxidative damage.

DOI: 10.1021/jf300359a
PubMed: 23252791

Affiliations:

Thaïlande

Le document en format XML

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<term>Cross-Over Studies</term>
<term>Diet</term>
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<front><div type="abstract" xml:lang="en">This study assessed the melatonin content of six tropical fruits and examined whether human consumption could contribute to dietary melatonin as measured by 6-sulfatoxymelatonin (aMT6-s, a marker of circulating melatonin in the body). Melatonin was extracted using methanol and analyzed by high-performance liquid chromatography. In a clinical crossover study, 30 healthy volunteers consumed selected fruits one at a time, with a 1week wash-out period between fruits, until completing all six fruits. Most fruits had moderate melatonin content. Significant increases in urine aMT6-s concentrations were seen after the consumption of pineapple (266%, p = 0.004), banana (180%, p = 0.001), and orange (47%, p = 0.007). The need to analyze melatonin both in fruit and as in vivo uptake was demonstrated. Further study is warranted regarding the clinical effect of fruit consumption in people with age-related melatonin reduction problems such as sleeplessness and illnesses involving oxidative damage.</div>
</front>
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Dietary intake of melatonin from tropical fruit altered urinary excretion of 6-sulfatoxymelatonin in healthy volunteers.

Dietary intake of melatonin from tropical fruit altered urinary excretion of 6-sulfatoxymelatonin in healthy volunteers.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

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